Topical Minoxidil (Loniten)  2% and 5%

Minoxidil (brand name Rogaine) was the first drug approved by the FDA for the treatment of male pattern baldness. It was initially developed as an oral medication for high blood pressure by Upjohn in the late 1950s. However, during clinical trials, researchers observed an interesting side effect – hair growth in unexpected places such as the face and hands. This led to the development of a topical minoxidil solution for treating hair loss, which Upjohn later obtained FDA approval for. In 1988, Upjohn launched Rogaine, a brand-name product containing minoxidil, as a treatment for hair loss. Initially, Rogaine was available in a 2% formulation, and later a higher strength 5% formulation was also approved by the FDA and introduced to the market. The 5% minoxidil solution is currently the most commonly used strength for treating hair loss.

While minoxidil has been clinically proven to slow the progression of hair loss and regrow some hair, most informed experts see it as a relatively marginally effective drug in the fight against hair loss. Since minoxidil has no effect on the hormonal process of hair loss, its positive effects are at best temporary and usually yield somewhat disappointing long-term results. However, it is still recognized as an effective treatment option for some individuals, especially when used in combination with other treatments such as finasteride.

In addition to the brand name Rogaine, there are also generic versions of minoxidil available, which contain the same active ingredient but may be marketed under different names by various pharmaceutical companies. These generic versions of minoxidil are often more affordable compared to the brand-name Rogaine, making them a popular option for many individuals seeking hair loss treatment.

Please note that the ownership of Upjohn has changed over the years. Upjohn was acquired by Pharmacia Corporation in 1995, and Pharmacia Corporation was then acquired by Pfizer in 2003. As of now, Pfizer is the current owner of the Rogaine brand.

Used for: Male Pattern BaldnessFemale Pattern Baldness